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Acetylated Low-Density Lipoprotein-Encapsulated Cholesteryl 1,3-Diiopanoate Glyceryl Ether for the Detection of Atherosclerosis in Rabbits

Wu Xiao, PhD1,2, Thomas M. Scott, PhD3, Liping Feng, MS1, Zhongshui Yu, BS1, Lili Wang, PhD1, Jeffrey A. Hughes, PhD2 and Hu Liu, PhD1,3

1 School of Pharmacy, Memorial University of Newfoundland, St. John’s, Newfoundland, Canada
2 Department of Pharmaceutics, College of Pharmacy, University of Florida, Gainesville, Florida
3 Faculty of Medicine, Memorial University of Newfoundland, St. John’s, Newfoundland, Canada



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FIGURE 1. Schematic diagram of route of synthesis of C2I.

 


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FIGURE 2. Results of Sudan IV staining (red staining, left panels) and autoradiography (black regions, right panels) of aortic samples taken at 24 h. (A) Samples from cholesterol diet group. (B) Sample from control group.

 





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