Somatostatin Receptor Scintigraphy in Liver Metastasis Detection from Gastroenteropancreatic Neuroendocrine Tumors
Orazio Schillaci, MD1,
Angela Spanu, MD2,
Francesco Scopinaro, MD3,
Antonio Falchi, MD2,
Roberta Danieli, MD1,
Pietro Marongiu, MD2,
Nicola Pisu, MD2,
Giordano Madeddu, MD4,
Gianfranco Delle Fave, MD5 and
Giuseppe Madeddu, MD2
1 Nuclear Medicine Division, University Tor Vergata, Rome, Italy
2 Department of Nuclear Medicine, University of Sassari, Sassari, Italy
3 Nuclear Medicine Unit, University La Sapienza, Rome, Italy
4 Department of Internal Medicine, University of Sassari, Sassari, Italy
5 Gastroenterology Division, University La Sapienza, Rome, Italy

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FIGURE 1. Patient 15 with ileal carcinoid, who previously underwent surgery and who developed single liver metastasis ascertained on histologic examination. Lesion is visible on SPECT SRS (single arrow) on transaxial, sagittal, and coronal views (A), whereas planar SRS and CIP (B, both CT and MRI) were negative.
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FIGURE 2. Patient 36 with pancreatic gastrinoma in whom abdominal SPECT SRS (A) reveals 2 liver metastases (single arrow), both visible on sagittal and coronal views. Only 1 liver metastasis is visible on transaxial view. Only 1 lesion is visualized by both planar imaging and MRI (B, double arrows). On CT view, negative for metastasis, primary tumor is visible.
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FIGURE 3. Patient 56 with rectal carcinoid in whom abdominal SPECT SRS (A) shows 2 liver metastases in 1 lobe (single arrow) on transaxial, sagittal, and coronal views, whereas planar SRS and CIP (B, both CT and MRI) are negative. Patient, who was classified as having NEM according to CIP data, was reclassified by SPECT SRS as having resectable metastases (RM) and underwent potentially curative surgery.
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Copyright © 2003 by the Society of Nuclear Medicine.