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L-1-¹¹C-Tyrosine PET in Patients with Laryngeal Carcinomas: Comparison of Standardized Uptake Value and Protein Synthesis Rate

¹ Departments of Otorhinolaryngology and Head and Neck Surgery, Groningen University Hospital, Groningen, The Netherlands
² PET Center of Groningen University Hospital, Groningen, The Netherlands

View larger version (74K): [in a new window]   FIGURE 1. Transaxial CT (A) and TYR PET (B) scans of T2 N2 M0 supraglottic laryngeal carcinoma (patient 13). Tumor (1) and metastatic lymph node (2) are clearly visualized. Note relatively low uptake of TYR in central necrosis of lymph node.

View larger version (22K): [in a new window]   FIGURE 2. Linear curve fits for relationship between PSR and SUVBW, SUVBSA, SUVLBM, and SUVQI. Significant correlations (P > 0.001; 2-tailed Pearson test) were observed between PSR and SUV corrected for BW (r = 0.87), BSA (r = 0.87), LBM (r = 0.90), and QI (r = 0.84).