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Whole-Body 18F-FDG PET Improves the Management of Patients with Small Cell Lung Cancer

Ehab M. Kamel, MD1, Daniel Zwahlen, MD2, Matthias T. Wyss, MD1, Katrin D. Stumpe, MD1, Gustav K. von Schulthess, MD, PhD1 and Hans C. Steinert, MD1

1 Division of Nuclear Medicine, Department of Medical Radiology, University Hospital Zurich, Zurich, Switzerland
2 Department of Radiation Oncology, University Hospital Zurich, Zurich, Switzerland



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  		FIGURE 1. Coronal (A) and transaxial (B) PET/CT scans of chest and thoracic aperture in 47-y-old female patient show left central LD SCLC with ipsilateral paratracheal and bilateral supraclavicular lymph node metastases (white arrows). (C) Transaxial CT scan at level of thorax aperture shows pathologically enlarged ipsilateral (large black arrow) and normal-sized contralateral (small black arrow) supraclavicular lymph nodes.

 


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  		FIGURE 2. Transaxial thoracic 18F-FDG PET scan (A) in 64-y-old male patient shows pathologic 18F-FDG uptake at lower lobe of left lung consistent with residual disease after 5 chemotherapy cycles (black arrow) with no corresponding CT scan abnormality (B). Follow-up CT scan at 7 mo (C) shows local recurrence at lower lobe of left lung (white arrows).

 


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  		FIGURE 3. Transaxial thoracic slices obtained by 18F-FDG PET (A), CT (B), and PET/CT (C) image fusion in 59-y-old female patient show residual disease after induction chemotherapy (arrows).

 




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