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Postsurgical Cerebral Perfusion Changes in Idiopathic Normal Pressure Hydrocephalus: A Statistical Parametric Mapping Study of SPECT Images

Maria Mataró, PhD1,2, Maria A. Poca, PhD2, Pilar Salgado-Pineda, PhD1, Joan Castell-Conesa, PhD3, Juan Sahuquillo, PhD2, Maria Jesús Díez-Castro, MD3, Santiago Aguadé-Bruix, PhD3, Pere Vendrell, PhD1, Maria del Mar Matarín, MS1 and Carme Junqué, PhD1,4

1 Department of Psychiatry and Clinical Psychobiology, University of Barcelona, Barcelona, Spain
2 Service of Neurosurgery, Vall d’Hebron University Hospital, Barcelona, Spain
3 Service of Nuclear Medicine, Vall d’Hebron University Hospital, Barcelona, Spain
4 Institut d’Investigacions Biomèdiques August Pi-Sunyer, Barcelona, Spain



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  		FIGURE 1. Postshunt improvement in gait, cognition, and sphincter functioning according to NPH scale.

 


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  		FIGURE 2. MR brain image shows areas of significantly increased perfusion. FLS = fasciculus longitudinalis superior; BA = Brodmann’s area.

 


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  		FIGURE 3. Image shows 2 areas most related to clinical improvement from regression analysis.

 




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