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Prognostic Value of Rest 201Tl-Dipyridamole Stress 99mTc-Sestamibi Gated SPECT for Predicting Patient-Based Clinical Outcomes After Bypass Surgery in Patients with Ischemic Left Ventricular Dysfunction

Won Jun Kang, MD1, Dong Soo Lee, MD1, Jin Chul Paeng, MD1, Ki-Bong Kim, MD2, June-Key Chung, MD1 and Myung Chul Lee, MD1

1 Department of Nuclear Medicine, Seoul National University College of Medicine, Seoul, Korea
2 Department of Thoracic Surgery, Seoul National University College of Medicine, Seoul, Korea



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FIGURE 1. Scatter plot showing pre- and postoperative LVEF values.

 


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FIGURE 2. ROC curve analyses for prediction of postoperative global functional improvement with each SPECT predictor. (A) Analysis by rest thallium uptake. (B) Analysis by reversibility score. (C) Analysis by measurement of preserved systolic wall thickening. (D) Analysis by delayed redistribution thallium uptake.

 


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FIGURE 3. ROC curve analysis for prediction of postoperative global functional improvement by logistic function encompassing rest thallium uptake and reversibility.

 


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FIGURE 4. Comparison of ROC curve for logistic function with that for rest thallium uptake.

 


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FIGURE 5. Event-free survival curves for patients in 2 groups. Patients with higher logistic function (>=0.84) were assigned to group A; those with lower logistic function (<0.84) were assigned to group B. Rate of cardiac events was higher in group B (P < 0.05).

 





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