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Changes in Cardiac Sympathetic Nerve Innervation and Activity in Pathophysiologic Transition from Typical to End-Stage Hypertrophic Cardiomyopathy

¹ Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Kanazawa University, Kanazawa, Japan
² Biotracer Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan

View larger version (22K): [in a new window]   FIGURE 1. Polar map of LV myocardium was divided into 20 segments as shown, and uptake and washout rate in each section were determined.

View larger version (33K): [in a new window]   FIGURE 2. Early uptake ratio and washout rate of 123I-MIBG in control group and in groups of patients with HCM.

View larger version (20K): [in a new window]   FIGURE 3. Polar maps depicting differences in relative 123I-MIBG early uptake between groups of patients with HCM. Ant = anterior wall; Lat = lateral wall; Post = posterior wall; Sept = interventricular septum.

View larger version (18K): [in a new window]   FIGURE 4. Polar maps depicting differences in relative 123I-MIBG washout rate between groups of patients with HCM. Ant = anterior wall; Lat = lateral wall; Post = posterior wall; Sept = interventricular septum.