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Inflammatory Bowel Disease Activity Assessment with Biologic Markers and ^99mTc-WBC Scintigraphy: Are There Different Trends in Ileitis Versus Colitis?

Department of Radiology, Children’s Hospital of Philadelphia, University of Pennsylvania, Philadelphia, Pennsylvania

View larger version (12K): [in a new window]   FIGURE 1. ESR vs. SAI in children with CD.

View larger version (139K): [in a new window]   FIGURE 2. Anterior projection of scintigraphy with 99mTc-WBC of 18 y old with CD that reveals increased uptake in sigmoid, ascending, and descending colon (ESR, 29 mm/h; WBC, 15.5 x 1,000 cells/mm3 µL; Alb, 2.9 g/dL).

View larger version (118K): [in a new window]   FIGURE 3. Anterior projection of scintigraphy with 99mTc-WBC of 11 y old with CD that reveals increased uptake limited to small bowel (ESR, 7 mm/h; WBC, 7.5 x 1,000 cells/mm3 µL; Alb, 4.1 g/dL).

View larger version (29K): [in a new window]   FIGURE 4. Concatenated graph of WBC vs. 99mTc-WBC uptake in terminal ileum, small bowel, ascending colon, transverse colon, descending colon, and sigmoid in children with CD.