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Visualization of Interscapular Brown Adipose Tissue Using 99mTc-Tetrofosmin in Pediatric Patients

Kazuki Fukuchi, MD1, Yasuo Ono, MD2, Yayoi Nakahata, MD2, Yoko Okada, MD2, Kohei Hayashida, MD1 and Yoshio Ishida, MD1

1 Department of Radiology, National Cardiovascular Center, Suita, Osaka, Japan
2 Department of Pediatrics, National Cardiovascular Center, Suita, Osaka, Japan



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  		FIGURE 1. Representative images of 99mTc-tetrofosmin uptake in neck and shoulder of patients of various ages: anterior planar images of upper body from 6-wk-old boy with dextrocardia (A), 6-y-old boy with double-outlet right ventricle (B), 14-y-old boy with ventricular septal defect (C), and 19-y-old man with Kawasaki disease (D). Arrows indicate symmetric 99mTc-tetrofosmin uptake in shoulder.

 


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  		FIGURE 2. Relationship between frequency of 99mTc-tetrofosmin uptake in interscapular BAT and age (years): number of studies (A) and frequency (B).

 


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  		FIGURE 3. Relationship between frequency of 99mTc-tetrofosmin uptake in interscapular BAT and season: number of studies (A) and rate of BAT uptake (B) during different seasons. Frequency is significantly greater in winter than in spring or summer.

 


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  		FIGURE 4. Serial 99mTc-tetrofosmin images of same patient at different seasons: images acquired in April 2002 (A) and December 2002 (B). Arrows indicate typical 99mTc-tetrofosmin uptake in interscapular BAT.

 




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