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Red Marrow Radiation Dose Adjustment Using Plasma FLT3-L Cytokine Levels: Improved Correlations Between Hematologic Toxicity and Bone Marrow Dose for Radioimmunotherapy Patients

Jeffry A. Siegel, PhD1, Dion Yeldell, BS2, David M. Goldenberg, ScD, MD2, Michael G. Stabin, PhD3, Richard B. Sparks, PhD4, Robert M. Sharkey, PhD2, Arnold Brenner, DO2 and Rosalyn D. Blumenthal, PhD2

1 Nuclear Physics Enterprises, Cherry Hill, New Jersey
2 Garden State Cancer Center, Belleville, New Jersey
3 Vanderbilt University School of Medicine, Nashville, Tennessee
4 CDE Dosimetry Services, Inc., Knoxville, Tennessee



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  		FIGURE 1. Comparisons of PN with FLT3-L–adjusted predictors of toxicity.

 


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  		FIGURE 2. Comparisons of 1/PN with FLT3-L–adjusted predictors of toxicity.

 




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