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Impact of Whole-Body ¹⁸F-FDG PET on Staging and Managing Patients for Radiation Therapy

¹ Division of Nuclear Medicine, Department of Medical Radiology, University Hospital, Zurich, Switzerland
² Clinic for Radiation Oncology, Department of Medical Radiology, University Hospital, Zurich, Switzerland

View larger version (136K): [in a new window]   FIGURE 1. A 75-y-old woman after resection of rectal carcinoma. Before PET, curative radiotherapy was planned. Coronal (A) and transverse (B) PET scans show previously unknown iliac internal lymph node metastasis (arrow). Correlating CT scan (C) does not show any metastases. Therapy concept was changed from curative to palliative treatment concept. Therefore, no irradiation but chemotherapy was given. After chemotherapy, PET was performed for restaging. Disappearance of abnormal 18F-FDG accumulation confirmed lymph node metastasis in initial PET study.

View larger version (117K): [in a new window]   FIGURE 2. A 50-y-old woman with lung cancer of right lower lobe. Before PET, primary curative radiotherapy was planned. Coronal (A) and transverse (B) PET scans show previously unknown contralateral mediastinal lymph node metastasis (arrow). (C) Lymph node metastasis is not seen primarily on CT scan. Because of PET, radiotherapy volume was increased.