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Increased Sensitivity in Detection of a Porcine High-Turnover Osteopenia After Total Gastrectomy by Dynamic 18F-Fluoride Ion PET and Quantitative CT

Morand Piert, MD1, Tilman T. Zittel, MD2, Michael Jahn2, Anke Stahlschmidt, PhD3, Georg A. Becker, PhD3 and Hans-Jürgen Machulla, PhD3

1 Nuclear Medicine, Technical University of Munich, Germany
2 Department of Abdominal and Transplantation Surgery, University of Tübingen, Germany
3 Radiopharmacy, PET-Center, University of Tübingen, Germany



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FIGURE 1. QCT image of porcine lumbar vertebra with oval ROI in center of vertebral body. According to reference CaHA standard, BMD was determined as 0.304 g/cm3 in this particular ROI.

 


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FIGURE 2. Transaxial 18F-fluoride ion PET image of lumbar vertebra in Figure 1 obtained after intravenous injection of 10.3 MBq/kg body weight of 18F-fluoride ion (image frame summation between 90 and 120 min). Oval ROI (ROI size, 1.1 cm2) is defined in center of vertebral body (image scale, 0–231 kBq/cm3).

 





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