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Detection of Neuroendocrine Tumors: 99mTc-P829 Scintigraphy Compared with 111In-Pentetreotide Scintigraphy

Rachida Lebtahi, MD, PhD1, Joseph Le Cloirec, MD2, Claire Houzard, MD3, Doumit Daou, MD1, Iradj Sobhani, MD, PhD4, Geneviève Sassolas, MD3, Michel Mignon, MD, PhD4, Patrick Bourguet, MD, PhD2 and Dominique Le Guludec, MD, PhD1

1 Nuclear Medicine Department, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, Paris, France
2 Nuclear Medicine Department, Centre Eugène Marquis, Rennes, France
3 Nuclear Medicine Department, Hôpital Universitaire Neuro-Cardiologique, Lyon, France
4 Gastroenterology Department, Hôpital Bichat, Assistance Publique-Hôpitaux de Paris, Paris, France



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  		FIGURE 1. Patient with nonfunctioning endocrine tumor. 111In-pentetreotide scintigraphy shows celiac tumors with liver metastases.

 


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  		FIGURE 2. Same patient as in Figure 1. Celiac tumoral and liver metastases are not shown by 99mTc-P829 scintigraphy.

 


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  		FIGURE 3. Patient with Zollinger-Ellison syndrome. 111In-pentetreotide scintigraphy shows multiple celiac tumors with liver and lung metastases.

 


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  		FIGURE 4. Same patient as in Figure 3. 99mTc-P829 scintigraphy shows lung metastases (smaller than those shown by 111In-pentetreotide scintigraphy). Celiac tumors are not detected. Liver metastases are not clearly seen.

 




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