JNM
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

This Article
Right arrow Abstract Freely available
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Right arrow reprints & permissions
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Nehmeh, S. A.
Right arrow Articles by Humm, J. L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Nehmeh, S. A.
Right arrow Articles by Humm, J. L.

Effect of Respiratory Gating on Quantifying PET Images of Lung Cancer

Sadek A. Nehmeh, PhD1, Yusuf E. Erdi, DSc1, Clifton C. Ling, PhD1, Kenneth E. Rosenzweig, MD2, Heiko Schoder, MD3, Steve M. Larson, MD3, Homer A. Macapinlac, MD4, Olivia D. Squire, RN3 and John L. Humm, PhD1

1 Department of Medical Physics, Nuclear Medicine Service, Memorial Sloan-Kettering Cancer Center, New York, New York
2 Department of Radiation Oncology, Nuclear Medicine Service, Memorial Sloan-Kettering Cancer Center, New York, New York
3 Department of Radiology, Nuclear Medicine Service, Memorial Sloan-Kettering Cancer Center, New York, New York
4 Department of Nuclear Medicine, The University of Texas, M.D. Anderson Cancer Center, Houston, Texas



View larger version (99K):

[in a new window]
  		FIGURE 1. Patient setup in gated mode.

 


View larger version (86K):

[in a new window]
  		FIGURE 2. Patient coordinate system.

 


View larger version (16K):

[in a new window]
  		FIGURE 3. Transaxial 18F-FDG PET image through 1 patient’s lesion in nongated mode (A) and corresponding image in gated mode acquired in first bin (B). (C) Planning target volume in nongated (light blue) and gated (pink) modes. Note that light blue extends under whole pink area. Gating, in this particular case, has mainly spared left lung tissues from high doses.

 


View larger version (50K):

[in a new window]
  		FIGURE 4. Comparison between lesion volumes in nongated and gated modes. Gating shows consistency in reducing apparent lesion volume.

 


View larger version (56K):

[in a new window]
  		FIGURE 5. Comparison between SUVmax in nongated and gated modes. Gating shows consistency in improving accuracy in SUVmax measurements.

 


View larger version (13K):

[in a new window]
  		FIGURE 6. Maximum TLG (TLGmax) measurements in gated mode show linear dependence on those measured in nongated mode because increase in SUVmax should result in reduction in lesion volume by same factor.

 


View larger version (35K):

[in a new window]
  		FIGURE 7. Maximum deviations of lesion centroids in x-, y-, and z-directions.

 




HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
JOURNAL OF NUCLEAR MEDICINE TECHNOLOGY THE JOURNAL OF NUCLEAR MEDICINE
Copyright © 2002 by the Society of Nuclear Medicine.