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Comparison of ¹¹C-Choline and ¹⁸F-FDG PET in Primary Diagnosis and Staging of Patients with Thoracic Cancer

¹ PET Center, Groningen University Hospital, Groningen, The Netherlands
² Department of Pulmonary Diseases, Groningen University Hospital, Groningen, The Netherlands

View larger version (45K): [in a new window]   FIGURE 1. Consecutive coronal planes of non–attenuation-corrected 18F-FDG PET (upper row) and 11C-CHOL PET (lower row) images. 18F-FDG images show intense uptake in primary tumor, hilar lymph node metastasis, and mediastinal lymph node metastases. 11C-CHOL-PET images show mild tracer uptake in primary tumor and hilar metastasis; the mediastinal lymph node metastases are missed. Note high uptake of 11C-CHOL-PET in liver and kidneys, hampering interpretation of upper abdomen.

View larger version (16K): [in a new window]   FIGURE 2. PET SUVs of 11C-CHOL and 18F-FDG of primary tumors in patients with thoracic cancer.