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A Retrospective Review of the Effectiveness of Recombinant Human TSH as a Preparation for Radioiodine Thyroid Remnant Ablation

Richard J. Robbins, MD1, Steven M. Larson, MD2, Naina Sinha, MD1, Ashok Shaha, MD3, Chaitanya Divgi, MD2, Keith S. Pentlow, PhD2, Ronald Ghossein, MD4 and R. Michael Tuttle, MD1

1 Endocrinology Service, Department of Medicine, Memorial Hospital for Cancer and Allied Diseases, Memorial Sloan-Kettering Cancer Center, New York, New York
2 Nuclear Medicine Service, Department of Radiology, Memorial Hospital for Cancer and Allied Diseases, Memorial Sloan-Kettering Cancer Center, New York, New York
3 Head and Neck Surgery Service, Department of Surgery, Memorial Hospital for Cancer and Allied Diseases, Memorial Sloan-Kettering Cancer Center, New York, New York
4 Division of Molecular Pathology, Department of Pathology, Memorial Hospital for Cancer and Allied Diseases, Memorial Sloan-Kettering Cancer Center, New York, New York



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  		FIGURE 1. Overview of diagnostic (Dx) and therapy time schedules. 131I-Dx, diagnostic radioiodine administration; 131I-Rx, therapeutic administration of 131I; RxWBS, whole-body scan after therapy. Letters in horizontal row of boxes indicate days of week.

 


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  		FIGURE 2. RRA rates in 2 groups: THW and rhTSH. Numbers above bars indicate exact percentage obtained for each category.

 


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  		FIGURE 3. Comparison of amount of 131I administered and final clinical outcome. (A) Group 1. (B) Group 2.

 




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