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Dual-Isotope SPECT Using 99mTc-Hydroxymethylene Diphosphonate and 201Tl-Chloride to Assess Mandibular Invasion by Intraoral Squamous Cell Carcinoma

Yuka Yamamoto, MD1, Yoshihiro Nishiyama, MD1, Katashi Satoh, MD1, Yumiko Ohbayashi, DDS2, Akinori Iwasaki, DDS2, Kazunori Miyabe, MD3 and Motoomi Ohkawa, MD1

1 Department of Radiology, Faculty of Medicine, Kagawa Medical University, Kagawa, Japan
2 Department of Oral and Maxillofacial Surgery, Faculty of Medicine, Kagawa Medical University, Kagawa, Japan
3 Department of Otolaryngology, Faculty of Medicine, Kagawa Medical University, Kagawa, Japan



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FIGURE 1. SPECT findings of 73-y-old woman with squamous cell carcinoma of left oral floor. Superimposed bone and tumor SPECT images show abnormal 99mTc-HMDP accumulation corresponding to tumor-positive sites in left mandible (arrow). Dual-isotope SPECT evaluation indicated invasion. Surgical result also indicated invasion.

 





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