PET Performance Measurements Using the NEMA NU 2-2001 Standard
Margaret E. Daube-Witherspoon, PhD1,
Joel S. Karp, PhD1,
Michael E. Casey, PhD2,
Frank P. DiFilippo, PhD3,
Horace Hines, PhD4,
Gerd Muehllehner, PhD5,
Vilim Simcic, PhD6,
Charles W. Stearns, PhD7,
Lars-Eric Adam, PhD1,
Steve Kohlmyer, MS7,8 and
Vesna Sossi, PhD9
1 Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania
2 CTI PET Systems, Knoxville, Tennessee
3 Picker International, Cleveland, Ohio
4 Philips Medical Systems, Milpitas, California
5 Philips Medical Systems, Philadelphia, Pennsylvania
6 Siemens Medical Systems, Hoffman Estates, Illinois
7 General Electric Medical Systems, Milwaukee, Wisconsin
8 Department of Radiology, University of Washington, Seattle, Washington
9 Department of Physics, University of British Columbia, Vancouver, British Columbia, Canada

View larger version (27K):
[in a new window]
|
FIGURE 1. Effect of acquisition and reconstruction sampling on transverse spatial resolution. FWHM values for central point source are shown for ADAC UGM C-PET scanner as function of radial sampling in sinogram and image pixel size. Following NU 2-2001 protocol, best spatial resolution would be measured; clinical parameters typically have 2- to 4-mm sinogram radial sampling and pixel size, which result in significantly degraded resolution on this system.
|
|

View larger version (54K):
[in a new window]
|
FIGURE 3. Representative image from image quality measurement for 6-min emission scan with hot sphere:background activity ratio of 8:1. Data were taken on ADAC UGM C-PET scanner and reconstructed with 3D RAMLA. Shown on right is placement of ROIs for quantitative analysis. Not shown is ROI for assessment of accuracy of corrections for attenuation and scatter, drawn on central lung-like cylindric insert.
|
|

View larger version (26K):
[in a new window]
|
FIGURE 4. Effect of reconstruction algorithm on image quality results taken on ADAC UGM C-PET scanner. Results for 1.7-cm hot sphere are shown for FBP for Hanning filters with cutoff frequencies ranging between 2 and 0.33 times Nyquist frequency as well as for ramp filter with cutoff at Nyquist frequency and 3D RAMLA for range of reconstruction parameters (number of iterations and relaxation parameter). Arrow shows results for parameters used in clinical studies. FORE = Fourier rebinning.
|
|
Copyright © 2002 by the Society of Nuclear Medicine.