Comparison of 123I Scintigraphy at 5 and 24 Hours in Patients with Differentiated Thyroid Cancer
Lalitha K. Shankar, MD, PhD1,
Alvin J. Yamamoto, MD1,
Abass Alavi, MD, MD1 and
Susan J. Mandel, MD, MPH2
1 Division of Nuclear Medicine, Department of Radiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
2 Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania
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FIGURE 1. Planar images obtained 5 h after 123I administration and before 131I therapy for thyroid remnant ablation. Mediastinal focus (arrow) detected on 5-h image (A) is not present on 24-h scan (B) or on scans after 131I therapy (not shown). Finding most likely represents focal retention of saliva 123I in esophagus.
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FIGURE 2. Planar images obtained 5 h (A) and 24 h (B) after 123I administration and 7 d after 131I therapy (C) in patient who was referred for thyroid remnant ablation. Right thyroid bed focus (dashed arrow) is not seen on 5-h image but is clearly present on 24-h image. Other foci of tracer activity in thyroid bed (left lower neck) and in right femur region (solid arrow) are better defined on 24-h image. Findings on 24-h image are confirmed by scan obtained 7 d after 131I therapy.
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FIGURE 3. Planar images acquired 5 h (A) and 24 h (B) after 123I administration and 7 d after 131I therapy (C) in patient with known pulmonary metastases who was scheduled to undergo thyroid remnant ablation. Five-hour and 24-h scans reveal bilateral pulmonary metastases (more clearly defined on posterior views than on anterior views), which appear more extensive and distinct on 24-h images than on 5-h images. Findings are confirmed by scan obtained 7 d after 131I therapy.
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FIGURE 4. Planar images obtained 5 h (A) and 24 h (B) after 123I administration and 7 d after 131I therapy (C) in patient with known pulmonary metastases 1 y after initial thyroid remnant ablation. Foci of uptake in lungs are faint on 5-h image but are clearly defined on 24-h image and are further confirmed by scan obtained 7 d after 131I therapy.
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Copyright © 2002 by the Society of Nuclear Medicine.
