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Heterogeneity of Cardiac Sympathetic Nerve Activity and Systolic Dysfunction in Patients with Hypertrophic Cardiomyopathy

¹ Molecular Genetics of Cardiovascular Disorders, Division of Cardiovascular Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan
² Biotracer Medicine, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan

View larger version (28K): [in a new window]   FIGURE 1. Left ventricular myocardium is divided into 20 segments, and uptake and washout rates in each section were determined.

View larger version (147K): [in a new window]   FIGURE 2. Polar maps of control subject (early image [A] and delayed image [B]) and patient with HCM (early image [C] and delayed image [D]).

View larger version (13K): [in a new window]   FIGURE 3. Segment shows maximal early uptake (A) and maximal washout rate (B). Black bars = patients with HCM; white bars = control subjects. Segments shown in Figure 1 are identified as follows: Ap = apical; AS = anteroseptal; AN = anterior; AL = anterolateral; IL = inferolateral; IN = inferior; IS = inferoseptal.

View larger version (23K): [in a new window]   FIGURE 4. (A) Relationship between early uptake dispersion and percentage of fractional shortening. (B) Relationship between SD of segmental early uptake and percentage of fractional shortening.