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Dual Time Point ¹⁸F-FDG PET Imaging for Differentiating Malignant from Inflammatory Processes

Divisions of Nuclear Medicine, Thoracic Surgery, and Pulmonary Medicine, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania

View larger version (66K): [in a new window]   FIGURE 1. Coronal images of same rat at early and late time point. White arrow points to inflammatory lesion; red arrow points to malignant lesion. Compared with early time point, SUV of inflammatory lesion in later time point decreased 25% and SUV of malignant lesion increased 16%. inj = injection.

View larger version (74K): [in a new window]   FIGURE 2. Comparison of early and delayed FDG PET images from 61-y-old man with lung carcinoma: transaxial images (A) and coronal images (B). Arrow points to lesion. Malignant focus became more apparent in later images and SUV increased from 3.77 to 5.55.