Evaluation of Early-Stage Parkinsons Disease with 99mTc-TRODAT-1 Imaging
Wen-Sheng Huang,
Shinn-Zong Lin,
Jiann-Chyun Lin,
Shiaw-Pyng Wey,
Gann Ting and
Ren-Shyan Liu
Departments of Nuclear Medicine, Neurological Surgery, and Neurology, National Defense Medical Center, Tri-Service General Hospital, Taipei; Department of Nuclear Medicine, Taipei Veterans General Hospital, Taipei; and Institute of Nuclear Energy Research, Lung-Tan, Taiwan, Republic of China

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FIGURE 1. 99mTc-TRODAT-1 SPECT in transverse views of healthy volunteer (A) and of patients with HYS stage I (B) and stage II (C) Parkinsons disease. Asymmetric striatal uptake was observed, with more profound loss contralateral to symptoms or more affected limbs.
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FIGURE 2. Specific striatal uptake of 99mTc-TRODAT-1 in healthy volunteers and in patients with HYS stage I and stage II Parkinsons disease.
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FIGURE 3. Specific putaminal uptake of 99mTc-TRODAT-1 in healthy volunteers and in patients with HYS stage I and stage II Parkinsons disease.
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FIGURE 4. Specific putaminal uptake of 99mTc-TRODAT-1 in healthy volunteers and in patients with HYS stage I Parkinsons disease contralateral and ipsilateral to symptoms.
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FIGURE 5. Specific putaminal uptake of 99mTc-TRODAT-1 in healthy volunteers and in patients with HYS stage II Parkinsons disease contralateral and ipsilateral to symptoms.
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FIGURE 6. Specific posterior putaminal uptake of 99mTc-TRODAT-1 in healthy volunteers and in patients with HYS stage I Parkinsons disease ipsilateral to symptoms.
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Copyright © 2001 by the Society of Nuclear Medicine.