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Pattern of Uptake and Excretion of 18F-FDG in the Lactating Breast

Rodney J. Hicks, David Binns and Michael G. Stabin

Peter MacCallum Cancer Institute Center for PET, Melbourne, Australia; and Vanderbilt University, Nashville, Tennessee



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  		FIGURE 1. FDG PET scan of patient 2579 acquired 65 min after administration of 60 MBq radiotracer demonstrates diffusely increased activity in both breasts. Representative transaxial (A), sagittal (B), and coronal (C) planes through right breast are shown. The images were processed with measured attenuation correction.

 


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  		FIGURE 2. FDG PET scanning on patient 186 was performed 50 min after intravenous administration of 100 MBq radiotracer. Representative images of the thorax without attenuation correction show diffuse and intense uptake of activity in left breast comparable to cardiac uptake but little uptake in right breast. The patient reported that her infant had refused to feed from right breast.

 


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  		FIGURE 3. FDG PET scan of patient 1420, 2 d after delivery of her child but before breast-feeding commenced. No medications had been given to suppress lactation. No increase in uptake is noted in breasts but intense uptake in mediastinal lymphoma is shown on these images acquired 70 min after 110 MBq radiotracer and processed with measured attenuation correction.

 




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