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Clinical Outcome of Patients with Previous Myocardial Infarction and Left Ventricular Dysfunction Assessed with Myocardial ^99mTc-MIBI SPECT and ¹⁸F-FDG PET

Departments of Nuclear Medicine, Surgery, and Cardiology, Cardiovascular Institute and Fu Wai Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, China

View larger version (49K): [in a new window]   FIGURE 1. 99mTc-MIBI SPECT and FDG PET images of patient with MI. (A) Perfusion–metabolism MM at apex, anterior, septal, and inferoposterior walls (arrows) before revascularization. (B) After CABG, perfusion defects of segments improved significantly and size of left ventricle decreased. EF increased from 30% to 42%. ST = stress; RE = rest.

View larger version (33K): [in a new window]   FIGURE 2. 99mTc-MIBI SPECT (A) and FDG PET (B) images of patient with MI show perfusion–metabolism M in inferoposterior wall (arrows) before revascularization. (C) After CABG, perfusion defects did not improve and EF did not change (38% vs. 39%).

View larger version (29K): [in a new window]   FIGURE 3. Changes of EF (%) and EDD (mm) at baseline (Pre), 3 mo (Pos1), and 6 mo (Pos2) after revascularization in groups A1 and B1.

View larger version (12K): [in a new window]   FIGURE 4. Cumulative cardiac event-free survival curves of groups A1 and A2 (A) and groups B1 and B2 (B). RVS = revascularization; Med = medical therapy.

View larger version (13K): [in a new window]   FIGURE 5. Cumulative survival curves of groups A1 and A2 (A) and groups B1 and B2 (B). RVS = revascularization; Med = medical therapy.

View larger version (12K): [in a new window]   FIGURE 6. Cumulative cardiac event-free survival curves of patients with aneurysm and viable myocardium (A) and patients with aneurysm and no viable myocardium (B). RVS = revascularization; Med = medical therapy.