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Occipital Brain Perfusion Deficits in Children with Major Depressive Disorder

Frederick J. Bonte, Madhukar H. Trivedi, Michael D. Devous, Sr., Thomas S. Harris, J. Kelly Payne, Warren A. Weinberg and Robert W. Haley

Nuclear Medicine Center; Departments of Radiology, Psychiatry, and Pediatrics; and Epidemiology Division, Department of Internal Medicine, University of Texas Southwestern Medical Center at Dallas, Dallas, Texas



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FIGURE 1. SPM maps of SPECT data from 8 patients with MDD and occipital defects and from 18 control subjects. Statistically significant data are projected onto midplane sections in each projection. Right frontal localizations are not statistically significant.

 


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FIGURE 2. SPM maps of SPECT data from 13 patients with MDD but no occipital defects and from 18 control subjects. Only data in right frontal region achieved statistical significance (Table 2).

 





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