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Uptake of Cis-4-[¹⁸F]Fluoro-L-Proline in Urologic Tumors

Institutes of Medicine and Nuclear Chemistry, Research Center Jülich, Jülich; and Clinics of Nuclear Medicine and Urology, Heinrich-Heine-University Düsseldorf, Düsseldorf, Germany

View larger version (102K): [in a new window]   FIGURE 1. PET and CT scans of 72-y-old man (patient 2) with left-sided renal clear cell carcinoma. (A) Reprojected whole-body scan using cis-FPro shows negative findings (dotted oval). Note uptake in renal cortex and pancreas. (B) Reprojected whole-body scan using FDG shows negative findings (dotted oval). (C) Transaxial CT scan at tumor level shows large, hypodense mass in left kidney.

View larger version (93K): [in a new window]   FIGURE 2. PET and CT scans of 81-y-old woman (patient 5) with left-sided renal squamous carcinoma. (A) Reprojected whole-body scan using cis-FPro shows relevant uptake neither in primary tumor nor in metastases (dotted oval). (B) Reprojected whole-body scan using FDG shows intensive uptake in primary tumor and regional lymph node metastases (dotted oval). (C) Transaxial CT scan at tumor level shows hypodense renal mass and enlarged para-aortic lymph nodes.