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Evaluation of Left Ventricular Function Using Electrocardiographically Gated Myocardial SPECT with ¹²³I-Labeled Fatty Acid Analog

Cardiovascular Center, Nagoya Daini Red Cross Hospital, Nagoya; and First Department of Internal Medicine and Department of Clinical Laboratory Medicine, Nagoya University School of Medicine, Nagoya, Japan

View larger version (16K): [in a new window]   FIGURE 1. Segmentation scheme used for regional assessment of defect scores and wall motion in SPECT.

View larger version (35K): [in a new window]   FIGURE 2. End-diastolic (ED) and end-systolic (ES) images obtained from gated SPECT with 123I-BMIPP (BM) and 99mTc-tetrofosmin (TF) in patient with anterior myocardial infarction.

View larger version (42K): [in a new window]   FIGURE 3. Comparison of LVEF (EF), LVEDV (EDV), and LVESV (ESV) obtained from gated SPECT with 123I-BMIPP (BM) and 99mTc-tetrofosmin (TF).

View larger version (41K): [in a new window]   FIGURE 4. (Left) Linear regression analysis of total defect score (TDS) of gated SPECT with 123I-BMIPP (BM) and differences between both gated SPECT procedures on LVEF (EF), LVEDV (EDV), and LVESV (ESV). TF = 99mTc-tetrofosmin. (Right) Linear regression analysis of TDS of gated SPECT with 123I-BMIPP and differences between gated SPECT with 123I-BMIPP and LVG on EF, EDV, and ESV.

View larger version (44K): [in a new window]   FIGURE 5. Comparison of LVEF (EF), LVEDV (EDV), and LVESV (ESV) obtained from gated SPECT with 123I-BMIPP (BM) and LVG.

View larger version (44K): [in a new window]   FIGURE 6. Comparison of LVEF (EF), LVEDV (EDV), and LVESV (ESV) obtained from gated SPECT with 99mTc-tetrofosmin (TF) and LVG.

View larger version (25K): [in a new window]   FIGURE 7. Linear regression analysis of LVEF (EF), LVEDV (EDV), and LVESV (ESV) on gated SPECT with 123I-BMIPP (BM) measured by 2 independent observers.