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Correlation of Tumor and Whole-Body Dosimetry with Tumor Response and Toxicity in Refractory Neuroblastoma Treated with ¹³¹I-MIBG

Departments of Pediatrics, Radiology, Epidemiology, and Biostatistics, University of California, San Francisco, San Francisco, California

View larger version (11K): [in a new window]   FIGURE 1. Comparison of whole-body radiation dose (cGy) calculated from exposure meter readings vs. whole-body dose (cGy) calculated from urine activity. P < 0.005.

View larger version (11K): [in a new window]   FIGURE 2. Correlation of administered activity of 131I-MIBG per kilogram of body weight with measured whole-body radiation dose. Spearman rank correlation, P < 0.0001.

View larger version (10K): [in a new window]   FIGURE 3. Correlation of TSARD with subsequent tumor volume decrease. Decrease in tumor volume is shown as positive percentage. Spearman rank correlation, P = 0.02.