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Serum Thyroglobulin Concentrations and 131I Whole-Body Scan Results in Patients with Differentiated Thyroid Carcinoma After Administration of Recombinant Human Thyroid-Stimulating Hormone

Alessia David, Annabella Blotta, Marta Bondanelli, Roberta Rossi, Elio Roti, Lewis E. Braverman, Luciano Busutti and Ettore C. degli Uberti

Section of Endocrinology, Department of Biomedical Sciences and Advanced Therapies, University of Ferrara, Ferrara; Radiotherapy Department, Malpighi Hospital, Bologna; Institute of Endocrinology, University of Milan, Milan, Italy; and Section of Endocrinology, Diabetes and Nutrition, Boston University, Boston, Massachusetts



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  		FIGURE 1. Protocol for rhTSH administration and radioiodine scanning procedure for patients on THST (148 MBq [4 mCi] 131I were administered).

 


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  		FIGURE 2. Serum TSH concentrations (mean ± SE) at baseline and after rhTSH injections during 5 d of study.

 


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  		FIGURE 3. Serum Tg levels at baseline and after rhTSH administration in 29 patients of group A (A) and in 4 patients of group B (B).

 


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  		FIGURE 4. Results of whole-body scanning and Tg measurements after rhTSH administration in 29 patients with baseline Tg levels of <2 ng/mL (group A) on THST.

 


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  		FIGURE 5. Results of whole-body scanning and Tg measurements after rhTSH administration in 4 patients with baseline Tg levels of >2 ng/mL (group B) on THST.

 




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