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The Diagnostic Value of ¹²³I-IMP SPECT in Non-Hodgkin's Lymphoma of the Central Nervous System

Department of Neurosurgery, Shimane Medical University, Izumo, Japan

View larger version (96K): [in this window] [in a new window]   FIGURE 1. A 69-y-old man with CNS lymphoma (patient 2). (A) T1-weighted MR image with gadolinium-diethylenetriaminepentaacetic acid shows homogenous enhancing lesions in midbrain and corpus callosum. (B) Midbrain tumor shows normal and high accumulation (arrowheads) on early (left) and delayed (right) SPECT images, respectively. (C) Early (left) and delayed (right) 123I-IMP SPECT images reveal increased uptake at corpus callosum.

View larger version (68K): [in this window] [in a new window]   FIGURE 2. A 52-y-old man with CNS lymphoma (patient 11). (A) T1-weighted MR image with gadolinium-diethylenetriaminepentaacetic acid shows heterogeneously enhancing mass in right parieto-occipital area. Mass is difficult to distinguish from high-grade glioma on MR image only. (B) 123I-IMP SPECT images show normal and increased accumulation (arrowheads) corresponding to tumor on early (left) and delayed (right) images, respectively.

View larger version (62K): [in this window] [in a new window]   FIGURE 3. A 72-y-old man with glioblastoma. (A) T1-weighted MR image with gadolinium-diethylenetriaminepentaacetic acid shows heterogeneously enhancing mass in left parietal region. (B) 123I-IMP SPECT images show defect (arrowheads) corresponding to tumor on both early (left) and delayed (right) images. T/Ns on early and delayed images are 0.23 and 0.21, respectively. T/Cs on early and delayed images are 0.18 and 0.20, respectively.

View larger version (95K): [in this window] [in a new window]   FIGURE 4. A 71-y-old woman with right parasagittal meningioma. 123I-IMP SPECT images show low accumulation and defect (arrowheads) corresponding to tumor on early (left) and delayed (right) images, respectively. T/Ns on early and delayed images are 0.53 and 0.48, respectively. T/Cs on early and delayed images are 0.18 and 0.14, respectively.