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The Journal of Nuclear Medicine Vol. 41 No. 10 1657-1663
© 2000 by Society of Nuclear Medicine
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FDG PET and Immunoscintigraphy with 99mTc-Labeled Antibody Fragments for Detection of the Recurrence of Colorectal Carcinoma

Petra Willkomm, Hans Bender, Michael Bangard, Pan Decker, Frank Grünwald and Hans-Jürgen Biersack

Departments of Nuclear Medicine and Surgery, University of Bonn, Bonn, Germany


Figure 1
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FIGURE 1. (A) FDG PET image (sagittal view) shows large area (arrow) with intense FDG accumulation behind bladder. (B) CEA-Scan (Immunomedics) image of same patient shows increased tracer accumulation in same area (arrow). Histologically, this area represented local recurrence.

 

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FIGURE 2. (A) In upper abdomen, FDG PET images (coronal, transversal, and sagittal views) show focally enhanced glucose metabolism with central defect. In lower abdomen directly above bladder, coronal view shows circular lesion with enhanced glucose metabolism in outer rim and central defect. Arrowheads point to local recurrence of liver metastases. (B) Liver SPECT study (CEA-Scan; Immunomedics) reveals similar result, with tracer uptake in viable tumor mass (arrowhead). High uptake is also seen in normal liver and myocardium. (C) High uptake is seen in abdomen, similar to FDG PET. Arrowhead points to local recurrence.

 





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