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The Journal of Nuclear Medicine Vol. 9 No. 6 249-259
© 1968 by Society of Nuclear Medicine
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Vascular Characterization of Brain Lesions by Rapid Sequential Cranial Scintiphotography

Mathews B. Fish, Myron Pollycove, Sean O'Reilly, Archie Khentigan and Robert L. Kock

San Francisco General Hospital and University of California School of Medicine, San Francisco, California

ABSTRACT

A technique is described for the detection and vascular characterization of intracranial lesions. This technique consists of the administration of 99mTc-pertechnetate (10 mc) by antecubital intravenous bolus injection followed by immediate rapid sequential and delayed scintiphotography using an Anger-type scintillation camera.

The results of multiple studies indicate that arterial capillary and venous phases can be visualized and distinguished. Analyses of these results provide mean time intervals for the various vascular phases on anterior and posterior viewing.

Representative studies from patients with a variety of intracranial lesions—primary neoplasm, cerebral infarct and subdural hematoma—are shown to demonstrate vascular and avascular lesions and their relationship to blood-brain-barrier abnormalities.

The advantages of this technique are discussed with emphasis on the great amount of relevant information obtained, the relative ease and speed of performance, patient safety and the possibility of acquiring data on the vascular characterization of intracranial lesions not obtainable by conventional brain-scanning or current methods of cerebral angiography.







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Copyright © 1968 by the Society of Nuclear Medicine.