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Simplified Method for Determining Glomerular Filtration Rate with ¹³¹I-Sodium Iothalamate

Comisión Nacional de Energía Nuclear, Mexico City, Mexico

Correspondence: For reprints contact: P. L. Eberstadt, Comisión Nacional de Energía Nuclear, Av. Insurgentes Sun 1236-2, Mexico 12, D.F., Mexico.

ABSTRACT

A single-injection method to determine glomerular filtration rate is presented. Sodium iothalamate labeled with ¹³¹I was used as an inulin-like substance. The method obviates the use of continuous intravenous infusions for administering the experimental reagent. One need not take blood samples. Furthermore, it is not necessary to insert a catheter into the bladder for urine specimens. We consider that the accuracy and obvious clinical advantages of the method we have presented render it fan more useful than other methods now employed.