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Some Biomedical Applications of a Non-Linear Curve Fit Method¹

Little Rock, Arkansas

ABSTRACT

A numerical method, applicable to some of the problem of non-linear curve fitting as it occurs in biology and medicine is described. Three different equations, theoretical considerations and a sample calculation are described. Given a proper model to describe the biological system, well-behaved data, convergence of solution and a sufficiently small residual variance, the investigator has objective justification that his data have been fitted by the model.

FOOTNOTES

¹ This research was supported by grants FR-00208-02 and NIH-FRS350-05 from the National Institutes of Health and NASA 04-001-014.

² Junior Medical Student, University of Arkansas Medical Center, Little Rock, Arkansas.

³ Associate Professor of Biometry, Univ. of Arkansas Medical Center, Little Rock, Arkansas.

⁴ Assistant Professor of Radiology and Physiology, Univ. of Arkansas Medical Center, Little Rock, Arkansas.

⁵ Professor and Chairman, Department of Anatomy, Univ. of Arkansas Medical Center, Little Rock, Arkansas.

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