HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

This Article Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Download to citation manager Citing Articles Citing Articles via Google Scholar Google Scholar Articles by Budabin, M. Articles by Siegel, G. J. Search for Related Content PubMed Articles by Budabin, M. Articles by Siegel, G. J.

The Anatomical Correlation of the Abnormal RIHSA Brain Scan¹

Chicago, Illinois

ABSTRACT

Comparison of the results of RIHSA brain scanning with the pathological findings in autopsied cases of meningioma, glioblastoma, and metastatic carcinoma, as well as in a single case of intracerebral hematoma, demonstrates the accuracy of localization of intracranial lesions by means of radioisotope examinations.

Despite complicating factors such as terminal hemorrhage, protracted clinical courses, and radiotherapy, the general estimation of the diameters of intracranial lesions by means of scanning usually proved to be within 1–2 cm of the actual measurements at the time of autopsy.

Lesions below 2.5 cm in diameter were usually not delineated by brain scanning. In addition, an even larger lesion in the posterior fossa eluded detection. Scanning was negative in a case of an infiltrating glioblastoma and in a case with a chondrosarcoma at the base of the skull. Cases with multiple areas of encephalomalacia and a case with multiple aneurysms also had negative scans.

These findings suggest that wider use of the abnormal brain scan should be made for the localization of lesions at the time of biopsy of the brain or for field localization if selective radiation therapy is planned.

FOOTNOTES

¹ Supported by grant number NB 05221 from the United States Public Health Service.

² Research Fellow in Neurology (Assigned to Physics).

³ USPHS Trainee in Neurology (USPHS grant number NB 5072).

⁴ From the Department of Neurology, the Department of Neuropathology and the Andre Meyer Department of Physics of the Mount Sinal Hospital, Chicago, Ill.