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The Hepatic Scan in Cirrhosis: Biochemical and Histologic Correlations^1,3,

Hines, Illinois

ABSTRACT

The factors influencing the appearance of the Rose Bengal or colloidal gold liver scans in cirrhosis are reduced hepatic blood flow, disturbed parenchymal function and the presence of areas of parenchymal replacement by necrosis, fatty infiltration, and fibrosis. These contribute to produce the diffuse, focal or diffuse plus focal appearance of the hepatic scan. A review of 40 cirrhotic patients with stabilized liver function tests showed that half had focal changes in their liver scan. These scans were not diagnostic though they were helpful in indicating a site for biopsy. There was a correlation of "diffuse" scan appearance with the degree of BSP retention. Also, post-necrotic cirrhosis was more likely to give the diffuse plus focal appearance than was Laennec's cirrhosis.

FOOTNOTES

¹ Address requests for reprints to: Radioisotope Service, Veterans Administration Hospital, Hines, Illinois.

³ From the Medical Service and Radioisotope Service, Veterans Administration Hospital, Hines, Illinois, and the Departments of Medicine, University of Illinois College of Medicine and Stritch School of Medicine, Loyola University.

² Present address: 59 King George Avenue, Jerusalem, Israel