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Effects of External Irradiation of the Heart on Cardiac Output, Venous Pressure and Arterial Pressure¹

College Station, and Brooks AFB, Texas

ABSTRACT

In summary, we would like to emphasize that doses of ionizing radiation in the therapeutic range may produce damage to the myocardium. The effect is probably an indirect effect resulting from increased permeability and fragility of the capillaries (9, 4, 3). The injury to the myocardium resulting from therapeutic doses may not be detected under normal resting conditions. Secondly, the latent period, time from exposure to microscopic changes in the cardiac muscle, is sensitive to small changes in dose.

FOOTNOTES

¹ This work was supported in part by the Atomic Energy Commission.

² Present address: Dept. Nuclear Engineering. Texas A&M University, College Station, Texas.

³ Present address: School of Aerospace Medicine, Brooks Air Force Base, San Antonio, Texas.