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The Journal of Nuclear Medicine Vol. 6 No. 8 598-604
© 1965 by Society of Nuclear Medicine
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Diagnosis of Hyperthyroidism by External Liver Counting: Correlation Between External Scintillation Counting of the Liver and Plasma Protein-Bound Iodine131

S. M. Sharma, M.B.B.S., D.M.R.T., K. B. Desai, B.Sc., K. P. Mehan, B.Sc., R. D. Ganatra, M.B.B.S., F.C.P.S., M.Sc., M. N. Mehta, B.Sc., K. Sundaram, M.D. and F. P. Antia, M.D., M.R.C.P.1

Bombay, India

ABSTRACT

External liver counting clearly distinguishes between euthyroid and hyperthyroid patients (t = 10.2); hyperthyroid and nontoxic goitre patients (t = 11.9). Individual values for these patients show a good separation between the groups. Correlation coefficient between liver counts and PBI131 in euthyroid and hyperthyroid patients was found to be 0.84 and correlation coefficient for hyperthyroid and nontoxic goitre patients was 0.76.

The advantages of external liver counting as an alternative method to plasma PBI131 estimations are:

  1. (a) Simplicity of the techniques;
  2. (b) No additional well scintillation assembly needed, and
  3. (c) No errors in results due to contamination of glassware, chemicals, etc.

FOOTNOTES

1 Radiation Medicine Centre, Medical Division, Atomic Energy Establishment Trombay, Tata Memorial Hospital, Parel, Bombay-12, India.







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Copyright © 1965 by the Society of Nuclear Medicine.