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The Retention by the Body of ¹³¹I-Polyvinylpyrrolidone and its Effect on Radiation Dose

Edinburgh, Scotland

ABSTRACT

It is shown that following the intravenous injection of PVP-¹³¹I, approximately half the material is excreted in the urine in the first 24 hours, while the remaining half is retained for a long time, mainly in the liver. The resulting rediation dose may be quite high when amounts required for brain scanning are administered. The use of the biological half-life to assess radiation dose is shown to be misleading under the circumstances described.

FOOTNOTES

¹ Department of Medical Physics, The Royal Infirmary, Edinburgh 3, Scotland.