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Tumor Localization in the Nasopharynx Using Radiomercury Labeled Chlormerodrin

Washington, D.C.

ABSTRACT

Tumors of the head and neck, in addition to brain tumors, localize radiomercury chlormerodrin and can be outlined on scintiscan. However, this technique was shown to be of limited value in determining the benign or malignant nature of a particular tumor. The degree of accuracy here in assuming the lesions with negative scans to be benign was 3 in 12 or 25 percent. In 25 malignancies, only 16 had positive scans with an accuracy of 64 percent. Except in one patient with juvenile angiofibroma, all of the tumors visualized were malignant. The scintiscan was positive in 16 of the 26 tumors ultimately shown to be malignant and 1 of the 4 tumors. One scan could not be interpreted because of interference from ¹³¹I remaining in neck following thyroid evaluation. The precise mechanism of isotope concentration has not been demonstrated.

FOOTNOTES

¹ Radioisotope Section

² Otolarynogology Service, Walter Reed General Hospital, Washington, D.C. 20012.