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Evaluation of Hepatic Photoscanning With Radioactive Colloidal Gold¹

San Francisco

ABSTRACT

A series of 100 consecutive photoscans of the liver with radioactive colloidal gold were reviewed and evaluated.

1. Of 15 hepatic scans showing space-occupying lesions for which anatomical diagnoses were available, 14 were confirmed histologically.

2. Marked discrepancy between the palpable inferior liver margin and the inferior margin of the scan image occurred in 4 cases; postmortem examination revealed massive metastatic replacement of the inferior portion of the liver, emphasizing the importance of the careful marking of organ and abdominal masses on the scan.

3. In 28 patients with cirrhosis, the study revealed no distinct correlation between the degree of abnormality shown by the liver function tests and the degree of "mottling." Splenic uptake was roughly correlated with the results of liver function tests. Marrow uptake was demonstrable in half of the patients with visible splenic uptake but was rarely observed in the absence of visible splenic uptake.

FOOTNOTES

¹ From the Department of Pathology, Clinical Laboratories, San Francisco General Hospital, University of California School of Medicine, San Francisco; the Donner Laboratory and the Lawrence Radiation Laboratory, University of California, Berkeley, California.

² At the time this work was carried out, Dr. Whang, a fellow of the International Atomic Energy Commission, was a guest scientist at the Donner Laboratory. His present address is: Kyung-Pook National University School of Medicine, Taegu, Korea.