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The Journal of Nuclear Medicine Vol. 6 No. 4 269-274
© 1965 by Society of Nuclear Medicine
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Renal Transit Time: Its Measurement by the 131I Hippuran Renogram

Fredric L. Coe, M.D. and Gerald Burke, M.D.1

Chicago

ABSTRACT

The mean renal transit time of hippuran can be calculated from the 131I hippuran renogram, and is the common denominator which explains the occurrence of a single renogram contour in a variety of disease states. Furthermore, several well known properties of mean transit time indicate that this parameter may be useful in characterizing the effects of disease upon both the permeability of renal parenchyma and the dynamics of urine flow. Finally, mean transit time must be distinguished from the first appearance time of hippuran in the urine.

FOOTNOTES

1 From the Radioisotope Laboratory and the Department of Metabolism and Endocrinology, Division of Medicine, Michael Reese Hospital and Medical Center, Chicago, Illinois.







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Copyright © 1965 by the Society of Nuclear Medicine.