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Evaluation of a Simple Technique for Abrupt Intravenous Injection of Radioisotope¹

Los Angeles

ABSTRACT

A simple, atraumatic technique of intravenous injection is described, which effects a dependably rapid deposition of isotope into the right heart.

Venous distention is caused in the arm distal to a partially inflated cuff. A small needle is placed in an antecubital vein and the cuff pressure raised above systolic. Tracer is injected into the isolated venous pool. Abrupt release into the right heart is produced by sudden removal of the constricting cuff while still inflated.

Average results on ten normal adult males subjects studied by this simple abrupt injection technique and later by simple rapid injection are compared using isotope passage through the cranial blood pool as the indicator of bolus compactness. The abrupt cuff-release method was shown to produce a more compact bolus than simple rapid injection. A total cranial detection system showed a head count which rises to a higher, sharper peak and falls off more rapidly.

FOOTNOTES

¹ This work was in part supported by USPHS Research Grant No. NB-02575.

² From the Neurology Section, Medical Service, Wadsworth Hospital, Veterans Administration center, Los Angeles, California (90073), and the Division of Neurology, Department of Medicine, UCLA Center for the Health Sciences, Los Angeles, California (90024).

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