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Patterns of Marrow Hypertrophy and Atrophy in Man

Berkeley, California

ABSTRACT

From positron camera studies of the gross distribution of erythropoietic marrow in patients with various hematologic diseases, it has become apparent that hypertrophy and atrophy of the marrow tend to follow a characteristic pattern. Both hypertrophy and atrophy frequently begin centrally and extend outward to the periphery of the skeleton. A classification of patterns based on three major stages of hypertrophy and three stages of atrophy is proposed.

FOOTNOTES

¹ From the Donner Laboratory of Medical Physics, Lawrence Radiation Laboratory, University of California, Berkeley, California.

² This work was supported in part by the United States Atomic Energy Commission and by Cancer Research Funds of the University of California.