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Principles of, and Pitfalls in, Thyroid Function Tests

Ann Arbor, Michigan

ABSTRACT

We have reviewed the physiological principles involved in the assessment of thyroid function by the following methods: 1) protein-bound iodine, 2) butanol-extractable iodine and thyroxine by columm chromatography. 3) thyroid radioactive iodine uptake, 4) thyroid stimulation tests, 5) thyroid suppression tests, and 6) triiodothyronine uptake by RBC or resin. Factors other than disturbances in thyroid function which affect these laboratory procedures are discussed with reference to the potential value of each test in certain clinical situations.

FOOTNOTES

¹ From the Department of Internal Medicine (Nuclear Medicine Unit), The University of Michigan, Ann Arbor, Michigan.