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⁷⁵Se Methionine as a Diagnostic Agent In Malignant Lymphoma¹

Danbury, Conn.

ABSTRACT

A group of malignant lymphomas exhibited a degree of uptake of ⁷⁵Se-L-Methionine which permitted their demonstration by means of photoscan. This property appears, at this time, not to be shared by epithelial neoplasms, either in original sites or lymph node metastases. Normal lymph nodes could not be demonstrated in this study. Malignant lymphomas which have been recently treated with surgery and/or exradiation failed to exhibit the above property. Of interest, was the lack of clinical evidence of recurrent activity in this last group.

If these preliminary observations can be confirmed by further studies, a valuable and safe technique will be available for the diagnosis of malignant lymphomas.

FOOTNOTES

¹ A Preliminary Communication

² Director of Laboratories, Danbury Hospital

³ Fellow, Department of Pathology, Danbury Hospital

⁴ Chief, Department of Medicine, Danbury Hospital Assistant Clinical Professor of Medicine, Yale University School of Medicine

⁵ Chief, Department of Radiology, Danbury Hospital

⁶ Director of Medical Education, Danbury Hospital Clinical Instructor of Medicine, Yale University School of Medicine