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Scintiencephalography for the Detection and Localization of Non-Neoplastic Intracranial Lesions^1,2,3

Iowa City, Iowa

ABSTRACT

Five hundred patients suffering from a variety of intracranial diseases were scanned using RIHSA, ¹³¹I colloidal human albumin or ²⁰³Hg chlormerodrin. A commercially available scanner with a three inch diameter NaI(TI) crystal, photorecorder and a color coded readout was used. Sixty-four of 75 confirmed neoplasms were correctly outlined by the scan. In 15 of 19 cases with a clinical diagnosis of cerebral infarction, the scans were abnormal when done within two weeks of the ictus. The incidence of abnormal scans decreased as the time interval between the onset of the infarction and the scan increased. Seven of eight arteriovenous malformations were correctly shown, as were five of five intracerebral hematomas, seven of eight subdural hematomas and one cholesteatoma. Areas of abnormal uptake of the isotope were found in four of four cases of craniocerebral trauma scanned within 14 days of injury.

FOOTNOTES

¹ From the Radiation Research Laboratory and the Department of Neurology, State University of Iowa, Iowa City, Iowa.

² Presented in part at the 11th Annual Meeting of the Society of Nuclear Medicine, Berkeley, California, June, 1964.

³ Supported in part by grants from the Iowa Division of the American Cancer Society.