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First published online February 11, 2010, 10.2967/jnumed.109.061853
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Journal of Nuclear Medicine Vol. 51 No. 3 333-336
© 2010 by Society of Nuclear Medicine

doi: 10.2967/jnumed.109.061853

Focus on Molecular Imaging

PET/MRI: Paving the Way for the Next Generation of Clinical Multimodality Imaging Applications

Bernd J. Pichler1, Armin Kolb1, Thomas Nägele2 and Heinz-Peter Schlemmer3

1 Laboratory for Preclinical Imaging and Imaging Technology of the Werner Siemens Foundation, Department of Radiology, University of Tübingen, Tübingen, Germany; 2 Department of Diagnostic and Interventional Neuroradiology, University of Tübingen, Tübingen, Germany; and 3 Department of Diagnostic and Interventional Radiology, University of Tübingen, Tübingen, Germany

Correspondence: For correspondence or reprints contact: Bernd J. Pichler, University of Tuebingen, Roentgenweg 11, Tuebingen, 72076 Germany. E-mail: bernd.pichler{at}med.uni-tuebingen.de

ABSTRACT

Multimodality imaging and, more specifically, the combination of PET and CT has matured into an important diagnostic tool. During the same period, concepts for PET scanners integrated into an MR tomograph have emerged. The excellent soft-tissue contrast of MRI and the multifunctional imaging options it offers, such as spectroscopy, functional MRI, and arterial spin labeling, complement the molecular information of PET. The development of a fully integrated PET/MRI system is technologically challenging. It requires not only significant modifications of the PET detector to make it compact and insensitive to magnetic fields but also a major redesign of the MRI hardware.

Key Words: clinical multimodality imaging • PET • CT • PET/CT • arterial spin labeling (ASL) • fMRI • spectroscopy • magnetic resonance tomograph (MRT) • PET/MRI • positron emission tomography • MR/PET

FOOTNOTES

COPYRIGHT © 2010 by the Society of Nuclear Medicine, Inc.


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