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First published online March 16, 2009, 10.2967/jnumed.108.053512
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Journal of Nuclear Medicine Vol. 50 No. 4 569-581
© 2009 by Society of Nuclear Medicine
doi: 10.2967/jnumed.108.053512

Continuing Education

The Role of Radiotracer Imaging in the Diagnosis and Management of Patients with Breast Cancer: Part 1—Overview, Detection, and Staging*

Jean H. Lee1, Eric L. Rosen2 and David A. Mankoff1

1 Department of Radiology, Seattle Cancer Care Alliance and University of Washington, Seattle, Washington; and 2 Seattle Radiologists, Seattle, Washington

Correspondence: For correspondence or reprints contact: David A. Mankoff, Seattle Cancer Care Alliance Radiology, G2-600, 825 Eastlake Ave., East Seattle, WA 98109. E-mail: dam{at}u.washington.edu

Breast cancer is the most common non-skin type of cancer and the second leading cause of cancer mortality in women. Advances in diagnosis and treatment have led to declines in mortality, despite an increase in breast cancer incidence. An advancing array of both local and systemic therapy options has led to increasingly individualized treatment. Imaging plays a key role in detecting breast cancer and directing its therapy. This continuing education article, part 1 in a 2-part series, provides a comprehensive review of current and future radiotracer imaging methods applied to breast cancer, in the context of breast cancer management strategies and other nonnuclear imaging methods. Part 1 of the review provides an overview of clinical and biologic considerations in breast cancer and covers radionuclide imaging for detection and staging. Part 2 will cover radionuclide imaging of breast cancer response to therapy, other clinical indications for radionuclide breast cancer imaging, and future directions, including molecular imaging.

Key Words: breast cancer • oncology • PET • nuclear medicine

* NOTE: FOR CE CREDIT, YOU CAN ACCESS THIS ACTIVITY THROUGH THE SNM WEB SITE (http://www.snm.org/ce_online) THROUGH APRIL 2010.

David Mankoff has indicated he receives scientific study/trial support from Pfizer and GE Healthcare. No other potential conflict of interest relevant to this article was reported.

COPYRIGHT © 2009 by the Society of Nuclear Medicine, Inc.


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Copyright © 2009 by the Society of Nuclear Medicine.