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¹⁸F-FDG PET and PET/CT in the Evaluation of Cancer Treatment Response^*

Institute of Nuclear Medicine University College London, London, United Kingdom

Correspondence: For correspondence or reprints contact: Simona Ben-Haim, Institute of Nuclear Medicine, University College London Hospital, NHS Trust, 235 Euston Rd. T5, London, NW1 2BU U.K. E-mail: Simona.ben-haim{at}uclh.nhs.uk

Multimodality imaging, as represented by its greatest exponent, PET/CT, has a firm place in the evaluation of a patient presenting with cancer. With ¹⁸F-FDG, PET/CT is rapidly becoming the key investigative tool for the staging and assessment of cancer recurrence. In the last 5 y, PET/CT has also gained widespread acceptance as a key tool used to demonstrate early response to intervention and therapy. In this setting, a major clinical need is being addressed with ¹⁸F-FDG PET/CT, because of its inherent ability to demonstrate (before other markers of response) if disease modification has occurred. This review presents available evidence to this effect.

Key Words: ¹⁸F-FDG • PET • PET/CT • tumor response • treatment monitoring • outcome

^* NOTE: FOR CE CREDIT, YOU CAN ACCESS THIS ACTIVITY THROUGH THE SNM WEB SITE (http://www.snm.org/ce_online) THROUGH JANUARY 2010.

The authors have indicated no relevant relationships that could be perceived as a real or apparent conflict of interest. No other potential conflict of interest relevant to this article was reported.

COPYRIGHT © 2009 by the Society of Nuclear Medicine, Inc.

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